ProfilerFAnalyzer for AOF by US EPA Method 1621

In January 2024, the US EPA published Method 1621, a screening method for the determination of adsorbable organic fluorine (AOF) in aqueous matrices by combustion ion chromatography (CIC). While CIC and LC-MS/MS both require sample preparation, measurement by CIC is slightly easier than LC-MS/MS and doesn’t require nearly as much data analysis and interpretation.

CIC System Workflow

Optimized for Fluorine Analysis

Following the multi-lab validation, the EPA finalized Method 1621 adding performance criteria. The ProfilerF Analyzer for AOF is configured specifically for AOF analysis, optimized to handle unknown fluoride concentrations. The system includes:

  • Patented combustion tube technology designed for fluorinated samples
  • EPA 1621 prescribed analytical and guard columns
  • Water delivery system capable of introducing reagent water at a controlled rate
  • Equipment for continuous eluent generation
  • MagIC Net software for seamless control of combustion and chromatography hardware
  • Comprehensive three-year warranty on full system


AOF Sample Prep by EPA Method 1621

Conveniently bundled with all the materials you’ll need to get started. This easy-to-use system helps you process up to 6 samples simultaneously. The bundle includes:

  • APU sim Sample Prep Unit made by Analytik Jena
  • Low-fluoride carbon extraction tubes
  • Sodium nitrate, >99%, 500g for preparing rinse solution
Additional Consumables available
  • Disposable syringes
  • O-rings
  • Replacement hoses
  • Duplex column holders
Request more information on EPA Method 1621
APUsim Setup and Calibration
APUsim Operation and Boat Loading